https://doi.org/10.4081/ltj.2022.305 Comprehensive approach to correct involutional-dystrophic skin changes in women PDF Vol. 29 No. 2 (2022) Published: 27 December 2022 Fibroblasts, platelet-rich plasma, aging, skin, skin wrinklings, laser ablation Abstract Views: 1877 PDF: 45 Publisher's note All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher. Authors Volodymyr Tsepkolenko Institute of Plastic Surgery, Odessa, Ukraine. Hanna Tsepkolenko office@virtus.ua Institute of Plastic Surgery, Odessa, Ukraine. Abstract Skin aging is one of the most urgent problems that is not being studied today. The study involved 107 women with signs of age-related changes in the skin of the face aged 25 to 60 years. They were treated according to our autor’s technology neofibrolifting - autologous fibroblasts transplantation into the pretreated with platelet-rich plasma skin and ablative fractional photothermolysis procedure. The developed neofibrolifting technology allows reconstructing authentic skin structure, improving its appearance and immunity. Metrics Dimensions Altmetric PlumX Metrics Downloads Download data is not yet available. Citations References Bonte F, Girard D, Archambault JC, Desmouliere A. Skin changes during ageing. Subcell Biochem 2019;91:249-80. DOI: https://doi.org/10.1007/978-981-13-3681-2_10 Castro MCR, Ramos-E-Silva M. Cutaneous infections in the mature patient. Clin Dermatol 2018;36:188-96. DOI: https://doi.org/10.1016/j.clindermatol.2017.10.010 Chambers ES, Vukmanovic-Stejic M. Skin barrier immunity and ageing. Immunology 2020;160:116-25. DOI: https://doi.org/10.1111/imm.13152 Kabashima K, Honda T, Ginhoux F, Egawa G. The immunological anatomy of the skin. Nat Rev Immunol 2019;19:19-30. DOI: https://doi.org/10.1038/s41577-018-0084-5 Laubach H., et al. Effects of skin temperature on lesion size in fractional photothermolysis. Lasers Surg Med 2007;39:14–8. DOI: https://doi.org/10.1002/lsm.20453 Nguyen AV, Soulika AM. The dynamics of the skin’s immune system. Int J Mol Sci 2019;20:1811. DOI: https://doi.org/10.3390/ijms20081811 Sandby-Moller J, Poulsen T, Wulf HC. Epidermal thickness at different body sites: relationship to age, gender, pigmentation, blood content, skin type and smoking habits. Acta Derm Venereol 2003;83:410-3. DOI: https://doi.org/10.1080/00015550310015419 Sarbacher CA, Halper JT. Connective tissue and age-related diseases. Subcell Biochem 2019;91:281-310. DOI: https://doi.org/10.1007/978-981-13-3681-2_11 Shin JW, Kwon SH, Choi JY, et al. Molecular mechanisms of dermal aging and antiaging approaches. Int J Mol Sci 2019;20:2126. DOI: https://doi.org/10.3390/ijms20092126 Citation / Copyright How to Cite Tsepkolenko, V., & Tsepkolenko, H. (2022). Comprehensive approach to correct involutional-dystrophic skin changes in women. Laser Therapy, 29(2). https://doi.org/10.4081/ltj.2022.305 More Citation Formats ACM ACS APA ABNT Chicago Harvard IEEE MLA Turabian Vancouver Download Citation Endnote/Zotero/Mendeley (RIS) BibTeX This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License. PAGEPress has chosen to apply the Creative Commons Attribution NonCommercial 4.0 International License (CC BY-NC 4.0) to all manuscripts to be published. 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