Reviews
Vol. 32 No. 2 (2025)
Efficacy and mechanisms of EndoliftX® in submental skin contraction
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All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher.
All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher.
Published: 12 December 2025
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This article evaluates the clinical efficacy, safety, and mechanistic insights of using the EndoliftX® laser device (Eufoton®, Trieste, Italy) with interstitial radial fibre delivery technology (ELX fibres, Eufoton®) for submental skin contraction. Through a detailed review of clinical and pre-clinical studies, we explore outcomes, including subcutaneous fat reduction, skin tightening, and collagen remodelling. The analysis includes procedural best practices, potential adverse effects, and patient satisfaction metrics, offering a comprehensive understanding of this minimally invasive procedure as an alternative to surgical neck lifting.
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CRediT authorship contribution
All authors certify that they have made substantial contributions to the work, accept public responsibility for its content, and have read and approved the final version of the manuscript.
Supporting Agencies
The manufacturer did not provide financial support for the study, except for covering the publication costs.Data Availability Statement
All data underlying the findings are fully available.
How to Cite
Fenech Magrin, A. M., Borg, N., & Ruffa, R. (2025). Efficacy and mechanisms of EndoliftX® in submental skin contraction. Laser Therapy, 32(2). https://doi.org/10.4081/ltj.2025.418
Copyright (c) 2025 the Author(s)
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